Explain why THC and CBD differ in their ability to elicit physiological effects.
Hints: Focus on actions in the brain (neuropharmacology) and effects outside the brain (peripheral effects) and pharmacological concepts of affinity/efficacy,
different receptor types, absorption, distribution, metabolism, and excretion, etc).
Cite at least two references and limit your response to 500-750 words.
Vandrey, R., Herrmann, E. S., Mitchell, J. M., Bigelow, G. E., Flegel, R., LoDico, C., & Cone, E. J. (2017). Pharmacokinetic Profile of Oral Cannabis in Humans:
Blood and Oral Fluid Disposition and Relation to Pharmacodynamic Outcomes. Journal of analytical toxicology, 41(2), 83–99.
https://doi.org/10.1093/jat/bkx012