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Pharmacokinetics and pharmacodynamic aspects of pharmacology
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
Sample Answer
Case Study: Patient with Hypertension
Patient: A 55-year-old male with a history of hypertension, type 2 diabetes, and obesity.
Current Medications:
- Lisinopril 20 mg daily
- Metformin 1000 mg twice daily
- Glyburide 5 mg daily
- Aspirin 81 mg daily
Blood Pressure: 145/90 mmHg
Goal: Reduce blood pressure to <130/80 mmHg
Evaluation of Drug Treatment Plan:
The patient’s current medication regimen includes a combination of antihypertensive agents, an antidiabetic agent, and an antiplatelet agent. However, the blood pressure remains elevated, indicating a need for adjustment.
Justification for Drug Therapy Plan:
- Lisinopril: An angiotensin-converting enzyme (ACE) inhibitor, lisinopril helps to lower blood pressure by blocking the formation of angiotensin II, a vasoconstrictor.
- Metformin: A biguanide, metformin helps to improve insulin sensitivity and reduce blood sugar levels.
- Glyburide: A sulfonylurea, glyburide stimulates insulin secretion from the pancreas.
- Aspirin: An antiplatelet agent, aspirin helps to reduce the risk of heart attack and stroke.
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