NCBI Chapter on Etiology

  1. Choose one of the genetic theories in chapter 2 and briefly summarize.
  2. Read the NCBI Chapter on Etiology – to an external site. and explain how this supplemented your knowledge on etiology of substance

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  • Genetics: There is a strong genetic component to substance use disorders. Studies have shown that people who have a family history of substance use disorders are more likely to develop these disorders themselves.
  • Neurobiology: Substance use disorders can also be caused by changes in the brain’s reward system. When people use substances, they release dopamine, a neurotransmitter that is associated with pleasure. Over time, the brain can become dependent on these substances to produce dopamine, leading to addiction.

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  • Environment: Environmental factors can also play a role in the development of substance use disorders. These factors can include things like poverty, abuse, and neglect.
  • Personality: People with certain personality traits, such as impulsivity and risk-taking, may be more likely to develop substance use disorders.
  • Stress: Stress can also be a trigger for substance use disorders. People who are under stress may be more likely to use substances as a way to cope with their feelings.

I already knew that genetics, neurobiology, and environment can all play a role in the development of substance use disorders. However, I learned a few new things from the NCBI chapter, such as the fact that personality traits and stress can also be contributing factors.

I also learned that the etiology of substance use disorders is complex and that there is no single cause. It is likely that a combination of factors, including genetics, neurobiology, environment, personality, and stress, contribute to the development of these disorders.

This information is important because it can help us to better understand the causes of substance use disorders and to develop more effective treatments. By understanding the factors that contribute to these disorders, we can develop interventions that target these factors and help people to overcome their addictions.


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