Gastrointestinal Function

R.H. is a 74-year-old black woman, who presents to the family practice clinic for a scheduled appointment. She complains of feeling bloated and constipated for the past month, some-times going an entire week with only one bowel movement. Until this episode, she has been very regular all of her life, having a bowel movement every day or every other day. She reports straining most of the time and it often takes her 10 minutes at a minimum to initiate a bowel movement. Stools have been extremely hard. She denies pain during straining. A recent colonoscopy was negative for tumors or other lesions. She has not yet taken any medications to provide relief for her constipation. Furthermore, she reports frequent heartburn (3–4 times each week), most often occur-ring soon after retiring to bed. She uses three pillows to keep herself in a more upright position during sleep. On a friend’s advice, she purchased a package of over-the-counter aluminum hydroxide tablets to help relieve the heartburn. She has had some improvement since she began taking the medicine. She reports using naproxen as needed for arthritic pain her hands and knees. She states that her hands and knees are extremely stiff when she rises in the morning. Because her arthritis has been getting worse, she has stopped taking her daily walks and now gets very little exercise.
Case Study Questions

In your own words define constipation and name the risk factors that might lead to develop constipation. List recommendations you would give to a patient who is suffering from constipation. You might use a previous experience you might have.
Based on the clinical manifestations on R.H. case study, name and explain signs and symptoms presented that are compatible with the constipation diagnosis. Complement your list with signs and symptoms not present on the case study.
Sometimes as an associate diagnosis and a complication, patients with constipation could have anemia. Would you consider that possibility based on the information provided on the case study?
Endocrine Function:
C.B. is a significantly overweight, 48-year-old woman from the Winnebago Indian tribe who had high blood sugar and cholesterol levels three years ago but did not follow up with a clinical diagnostic work-up. She had participated in the state’s annual health screening program and noticed that her fasting blood sugar was 141 and her cholesterol was 225. However, she felt “perfectly fine at the time” and could not afford any more medications. Except for a number of “female infections,” she has felt fine until recently. Today, she presents to the Indian Hospital general practitioner complaining that her left foot has been weak and numb for nearly three weeks and that the foot is difficult to flex. She denies any other weakness or numbness at this time. However, she reports that she has been very thirsty lately and gets up more often at night to urinate. She has attributed these symptoms to the extremely warm weather and drinking more water to keep hydrated. She has gained a total of 65 pounds since her last pregnancy 14 years ago, 15 pounds in the last 6 months alone.
Case Study Questions

In which race and ethnic groups is DM more prevalent? Based on C.B. clinical manifestations, please compile the signs and symptoms that she is exhibiting that are compatible with the Diabetes Mellitus Type 2 diagnosis.
If C.B. develop a bacterial pneumonia on her right lower lobe, how would you expect her Glycemia values to be? Explain and support your answer.
What would be the best initial therapy non-pharmacologic and pharmacologic to be recommended to C.B?

Full Answer Section

       

Recommendations for Constipation:

  • Increase Fiber Intake: Aim for 25-35 grams of fiber daily through fruits, vegetables, and whole grains.
  • Hydration: Drink plenty of fluids throughout the day to soften stool.
  • Exercise Regularly: Even moderate activity can improve gut motility.
  • Establish a Bathroom Routine: Try to have a bowel movement around the same time each day, allowing for relaxation and time.
  • Over-the-counter laxatives: Can provide short-term relief, but consult a doctor for long-term use.

Signs and Symptoms of R.H.'s Constipation:

  • Bloating
  • Straining during bowel movements
  • Hard stools
  • Infrequent bowel movements (less than once a week)
  • Time required to have a bowel movement (10 minutes or more)

Additional Signs and Symptoms of Constipation not present in R.H.'s case:

  • Rectal pain
  • Abdominal pain
  • Feeling of incomplete bowel evacuation

Anemia and R.H.'s Constipation:

Based solely on the information provided, anemia is unlikely. However, chronic constipation can sometimes lead to iron deficiency anemia due to difficulty absorbing iron from food. A blood test would be needed to confirm anemia.

Case Study 2: C.B.

Diabetes Mellitus (DM) Prevalence:

Type 2 diabetes is more prevalent in certain racial and ethnic groups, including Hispanic/Latino, African American, Native American, and Asian American populations.

Signs and Symptoms of C.B.'s Type 2 Diabetes:

  • Increased thirst (polydipsia)
  • Frequent urination (polyuria)
  • Excessive hunger (polyphagia)
  • Weight gain
  • Fatigue
  • Numbness and weakness in the foot (potential neuropathy)

Glycemia and Bacterial Pneumonia:

If C.B. develops bacterial pneumonia, her blood sugar levels (glycemia) are likely to be elevated. Stress hormones released during infection can increase blood sugar levels. This highlights the importance of managing diabetes to prevent complications like infections.

Initial Therapy for C.B.'s Type 2 Diabetes:

Non-pharmacologic:

  • Diet and Exercise: A balanced diet and regular physical activity are crucial for managing blood sugar levels.
  • Weight Management: Losing weight can significantly improve blood sugar control in overweight or obese individuals.

Pharmacologic:

  • Oral Medications: Metformin is a common first-line medication for type 2 diabetes. Other medications may be added based on individual needs.

Remember, this information is intended for educational purposes only and should not be interpreted as medical advice. Always consult with a healthcare professional for diagnosis and treatment

Sample Answer

     

Case Study 1: R.H.

Constipation: Constipation is defined as difficulty passing stool, infrequent bowel movements (less than three per week), or hard, dry stools.

Risk Factors for Constipation:

  • Diet: Lack of fiber, dehydration, excessive dairy intake
  • Lack of Exercise: Physical inactivity can slow down digestion.
  • Medications: Opioids, antidepressants, diuretics, some iron supplements
  • Medical Conditions: Hypothyroidism, diabetes, neurological disorders
  • Muscle weakness: Especially in the pelvic floor muscles